I just created a new presentation and put in a couple of test links. One to google and another to a picture on my computer. Can't click on either. Straightforward links, no commas or other special characters or spaces.
A few days ago when I was trying to narrow or widen the issue I found I couldn't click on hyperlinks in a word document. Finally found out I had to disable the option from cntrl-click. I was hoping there was something like this in Powerpoint but there
doesn't seem to be. I am going to take this presentation to the site where I will be giving it tomorrow to see what happens there.