A family of Microsoft relational database management systems designed for ease of use.
What is the file extension of the file you are trying to open?
If the database was originally created on 32-bit and now you wish to use it on 64-bit, then APIs needs to be updated, ActiveX, ... Refer to
https://www.devhut.net/2017/04/13/access-x32-vs-x64-compatibility/
The easier option is to uninstall office and reinstall the 32-bit version as 64-bit offers little to no advantages for the average user and instead causes all sorts of headaches.