A family of Microsoft presentation graphics products that offer tools for creating presentations and adding graphic effects like multimedia objects and special effects with text.
>> my PC opens up the magnifier settings (screenshot attached).
No screenshot here, I'm afraid. Try just pasting it into your reply instead of using the image tool on the toolbar here.
If this is the Windows Magnifier, it uses Ctrl+Alt+M to cycle through different magnifier views, and probably "grabs" the keystrokes before any other programs (e.g. PowerPoint) "see" them.
If you don't need to use Windows Magnifier, quit it; that should give the shortcut sequence back to PowerPoint. If you need a magnifer AND want to use the same shortcut keys for comments, you might need to find an alternate magnifier program.