It is best practice to use an extra disc with host cache disabled for the NTDS.dit and SYSVOL for DCs.
With host cache on it could last, if i remember right, up to 15 minutes until the cache is written back to the disk.
If the host has any trouble you might loose up to 15 minutes of AD related changes.
After the VM is running again you might get trouble with different update sequence numbers on the domain controllers in AD in an AD replication scenario.
So i would recommend the best practice for DCs with the second disk and disabled host cache. Depending on the size of the NTDS.dit and SYSVOL the additional costs of a 8 or 16 GB disk should not be a problem.
Maybe this is helpful.
Regards
Andreas Baumgarten
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