Interesting. At this point, testing from a Linux USB stick will confirm if this is hardware or Windows-related. You could also contact Dell Support to help isolate possible hardware faults.
You can find helpful steps here.
Note: This is a non-Microsoft website. The page appears to be providing accurate, safe information. Watch out for ads on the site that may advertise products frequently classified as a PUP (Potentially Unwanted Products). Thoroughly research any product advertised on the site before you decide to download and install it.
If you have more than one monitor, disconnect all but one to rule out multi-monitor DPI scaling issues.
You can also try disabling mouse acceleration fully in the registry. Backup your registry first (File > Export in regedit) because incorrect changes can cause system issues.
Press Win+R, type regedit, and press Enter
Go to HKEY_CURRENT_USER\Control Panel\Mouse
Set MouseSpeed to 0, MouseThreshold1 to 0, and MouseThreshold2 to 0
Restart your PC