Let's move beyond the basic checks and into more advanced, targeted solutions that have proven effective in complex environments like yours.
Solution 1: The Nuclear Option - Use a Third-Party Utility For a 12-monitor setup, a dedicated utility is often the most robust and time-saving solution. Tools like DisplayFusion or Actual Multiple Monitors are specifically designed to solve this exact problem. Their primary function is to save and lock monitor profiles (including position, resolution, and icon layout) and automatically re-apply them on wake-up or login. This is the most reliable way to fight Windows' native behavior.
Solution 2: Deep Dive into GPU Driver Settings (NVIDIA/AMD) The generic Windows drivers are not built for this scale. You need to leverage your GPU's control panel.
- For NVIDIA: Open the NVIDIA Control Panel, go to "Set up multiple displays." Right-click in the display arrangement section and "Save Display Configuration." You can then set up a task in Windows Task Scheduler to run the saved
.bin file on logon/unlock.
For AMD: Use the AMD Software to create and save a "Display Profile." Ensure the profile is set to auto-apply.
Solution 3: Prevent Driver Resets via Power Management The driver is likely being fully reset during sleep. We can try to disable this:
Open Device Manager.
Expand "Monitors" and for each generic "PnP Monitor" listed, right-click, select Properties, go to the Driver tab, and click Disable. This prevents Windows from "rediscovering" them and forcing a reset. (You may need to do this for your graphics adapter under "Display adapters" as well, looking for a "Power Management" tab to uncheck "Allow the computer to turn off this device to save power").
Solution 4: The Registry Hack (Use with Caution) This tells Windows not to use a default configuration if detection fails.
Press Win+R, type regedit, and press Enter.
Navigate to: HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Control\GraphicsDrivers\Configuration
Right-click the Configuration key, select Permissions, click Advanced, and set the owner to your user account. Then, give your user Full Control over this key and all its subkeys. This can prevent permission issues that block profile saving.
I recommend starting with Solution 1 (DisplayFusion) as it is purpose-built for this and will save you endless hours of manual reconfiguration. The other solutions are more surgical but can be combined if necessary.
I truly hope one of these advanced methods finally provides a stable solution for your impressive setup. If one of these approaches works, please share the results here to help the hundreds of other users facing this same challenge.