A Microsoft communications service that provides communications capabilities across presence, instant messaging, audio/video calling, and an online meeting experience that includes audio, video, and web conferencing.
In our environment, we created a Group Policy with two items configured.
First, with the "Administrative Template files (ADMX/ADML) for Microsoft Office" installed (https://www.microsoft.com/en-us/download/details.aspx?id=49030), we configured:
User Configuration > Policies > Administrative Templates... > Skype for Business 2016 > Microsoft Lync Feature Policies
"Prevent users from running Microsoft Lync" - Enabled
Then, we added a registry setting under:
User Configuration > Preferences > Registry
New > Registry Item
Action: Delete
Hive: HKEY_CURRENT_USER
Key Path: Software\Microsoft\Windows\CurrentVersion\Run
Value name: Lync