Hi @Rizwan Assad
Thank you for posting your question in the Microsoft Q&A forum.
For creating Exchange Online mail flow rule, you may go to EAC > Mail flow > Rules to create a mail flow rule. After setting the condition, you can choose “Modify the message properties > set the spam confidence level (SCL)” and select “Bypass spam filtering”.
Please check this for more details: Use mail flow rules to the SCL in messages in Exchange Online | Microsoft Learn
Additionally, please understand that our Exchange Online Q&A forum only focus on issues related to Exchange Online services. If you need more suggestions about Microsoft Defender, you can post questions under “Microsoft Defender” related tags. Thanks for your understanding.
Microsoft Defender for Cloud - Microsoft Q&A
If the answer is helpful, please click "Accept Answer" and kindly upvote it. If you have extra questions about this answer, please click "Comment".
Note: Please follow the steps in our documentation to enable e-mail notifications if you want to receive the related email notification for this thread.