Hi KevinPark,
A mouse with a USB adapter does have latency advantages over a Bluetooth mouse, but these advantages are negligible if you're not playing games.
However, I think that even if the Bluetooth mouse will have a certain delay, there should not be a random loss of response, which depends on whether the problem is specific to this mouse or is related to the abnormal Bluetooth function of the Surface.
To determine the source of the problem, you may still need to do some tests, such as pairing the Bluetooth mouse with other laptops to check if the lost response problem will occur again.
Best Regards,
Mitchell | Microsoft Community Support Specialist