Hello azapata59,
I would just leave it off unless you connect an iSCSI device to the computer or network NAS, in which case you can enable it at that time. The iSCSI Initiator service allows Vista to connect to SCSI devices attached to a network. See more information on Microsoft’s iSCSI implementation here: http://www.enterprisestorageforum.com/technology/features/article.php/1547831. Hope this helps you. Let us know either way. Make it a great day!
"And In The End The Love You Take, Is Equal To The Love You Make" (The Beatles last song from thier last album, Abbey Road.)