Hi Hagar83,
Welcome to Microsoft Answers.
• When do you get this error message?
You may try these:
A) A clean boot helps eliminate software conflicts.
The following link has steps showing how to perform clean boot. http://support.microsoft.com/kb/929135
1) Perform clean boot
i. Click Start, type msconfig in the Start Search box, and then press ENTER.
If you are prompted for an administrator password or for a confirmation, type the password, or click Continue.
ii. On the General tab, click Selective Startup.
iii. Under Selective Startup, click to clear the Load Startup Items check box.
iv. Click the Services tab, click to select the Hide All Microsoft Services check box, and then click Disable All.
v. Click OK.
vi. When you are prompted, click Restart.
vii. After the computer starts, check whether the problem is resolved.
2) Enable half of the services
3) Determine whether the problem returns
4) Enable half of the startup items
5) Determine whether the problem returns
6) Repeat the above steps until you find out which service or program is causing the issue
After you determine the startup item or the service that causes the problem, contact the program manufacturer to determine whether the problem can be resolved. Or, run the System Configuration Utility, and then click to clear the check box for the problem item.
Note: Please ensure that the computer is set to start as usual by following the step 7 from the article http://support.microsoft.com/kb/929135 .
Reset the computer to start as usual
After you have finished troubleshooting, follow these steps to reset the computer to start as usual:
i. Click Start, type msconfig.exe in the Start Search box, and then press ENTER. If you are prompted for an administrator password or for confirmation, type your password, or click Continue.
ii. On the General tab, click the Normal Startup option, and then click OK.
B) Change the drive letter assignment for the removable drive to a letter other than C.
- Open Computer Management by clicking the Start button, clicking Control Panel, clicking System and Maintenance, clicking Administrative Tools, and then double-clicking Computer Management. If you are prompted for an administrator password or confirmation, type the password or provide confirmation.
- In the Navigation pane, click Disk Management.
- Right-click the partition or drive that you want to change, and then click Change Drive Letter and Paths.
- Do one of the following:
•To assign a drive letter if one has not already been assigned, click Add, click the letter that you want to use, and then click OK.
•To change a drive letter, click Change, click Assign the following drive letter, click the letter that you want to use, and then click OK.
•To remove a drive letter, click Remove, and then click Yes to confirm that you want to remove it.
Check the article “There Is No Disk in the Drive. Please Insert a Disk into Drive \Device\harddisk\Dr1" Error Message When You Start Your Computer” http://support.microsoft.com/kb/330137
Diana
Microsoft Answers Support Engineer
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