According to this forum post, you need to uninstall it:
Go to Control Panel, then to Programs, then to Uninstall a Program. Look for the Dell Datasafe programs. Uninstall them. The popup will go away.
http://en.community.dell.com/support-forums/virus-spyware/f/3521/t/19374460.aspx
In that same thread, a Microsoft MVP strongly recommends you do not uninstall it, but instead, resolve the issues presented by the 'My Dell Downloads' pop up