Hi,
· Are you referring to the .386 file extension?
Step 1: If yes, you need not have to worry about and also it cannot be removed.
A 386 file is a system file used by older Windows 3.x systems. It enables certain hardware components to run correctly. "386" comes from the type of processor used in many early Windows machines.
Step 2: If that’s not the one you are referring to, then please post a screen shot of what exactly you are looking at so that we can help you better. Check the link mentioned below.
Use Skydive to upload collected files and post screen shot/picture.