Hi,
We need to make sure a certain folder path is in your path environment variable.
Let us determine the correct path to add into the Path environment variable. Look in C:\Windows\twain_32 and there should one other folder in there. For example the folder name should be CNQ4803.
This is the path that is needed to be added into the path environment variable.
C:\Windows\twain_32\CNQ4803
Now, follow these instructions to get to the dialog to modify the path environment variable.
a.Control Panel > System > and then choose Advanced System Settingsin the left hand column.
b. This will bring up the System Propertiesdialog (it should already be on the Advancedtab).
c. At the bottom of this dialog is an Environment variablesbutton. Clicking this button will bring up the Environment variables dialog.
d. In the bottom panel, scroll until you find the variable named path. Select this one and then hit the Edit button to bring up the Edit System variable dialog.
e. In the Variable value text box, scroll all the way to the right and then add in the path C:\Windows\twain_32\CNQ4803that was determined earlier. Make sure to separate this value with a preceding semi-colon. And also be careful not to make any other changes to this value.
Now click on OK and check if it works.
If the issue still persists, I would suggest you to contact Canon support for more information:
http://www.usa.canon.com/cusa/support
Hope this helps.