Other Configuration Manager-related features and issues
Hi, @Abdo Ismail
Thank you for posting in Microsoft Q&A forum.
For client management activities, ConfigMgr neither relies on or requires AD in any way, so multiple domains or forests with or without trusts are irrelevant.
For more details about SCCM multiple domains management, you may read Jason's great article:
https://www.1e.com/news-insights/blogs/mvp-questions-answered/
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