What is the BEST Registry Cleaner for Win 7 Ultimate or Pro 64 Bit version OS ?

It's pretty amazing how reg cleaning is totally unnecessary, yet someone like me, a computer professional for 20 years does the following:

1.  buys new windows machine.

2.  installs good anti-virus protection (Eset)

2.  never installs extra or junky software

3.  makes sure it's constantly defragged

and experiences the following:

1.  consistent system slowdowns after 4 hours of runtime

2.  webpages that cause complete system freeze for minutes at a time

3.  random crashes doing completely innocuous things

4.  webpages non-responsive to input

5.  5 solid minutes to go to sleep, with each successive sleep causing additional system glitch

6.  authoritarian updater that unilaterally decides the time my machine will be unresponsive/disabled for 15 minutes at a time.

7.  160.00 bill to fix a busted power line jack

Meanwhile, my wife's beautiful MacBook Pro, bought around the same time, functions absolutely flawlessly, day in and day out.

man, I'm DONE with paying for microsoft operating systems.

Though I haven't bought it myself, Dell recommends iola. (mispelled, it should be iolo system mechanic as per below post).  I don't know if registry cleaners are as bad as some here say they are, I do know I had a registry cleaner on my XP and was glad for it.  It definitely did speed up the computer, and I noticed no glitches because of it.  However, I'd have to tell you I believe the most likely reason a computer slows down are viruses;  this is what I'm told, over and over again, so it must be true.  If you do buy a registry cleaner, you'll be wise to make sure your system restore feature is running well; that way, if the cleaner does create a glitch, you can restore the computer to just before it happened.  Try to buy a registry cleaner which you can set to create a restore point before it does anything, then make sure you've turned it on before using it.  Then perhaps you can have the best of both worlds, so to speak. Good luck.

You are misinformed. If you have factual data to backup your conjecture please provide it. The manufactures of these snake oil can't provide anything but marketing hype.

I think the issues you may be referring to are ancient history. If it was windows 98 I might agree with you.

We see many problems with these products removing critical windows files rendering windows not genuine. usually requiring a reinstall.

Windows 9x required a registry cleaner to remove safe and orphaned entries, and Microsoft made one called RegClean 4.

It worked well because Windows 9x registry would 'fall over' if it became to large.

OK. lets move on to Windows 9x's cousins (not direct relatives)

Windows 2000, XP, Vista and 7 registry does not have the original shortfalls of the Windows 9x registry. The new registry can get way larger than any user is ever likely to manage. Also, the four operating systems all ignore orphaned entries, unlike Windows 9x which read and tried to execute them all.

In this way, registry cleaners have had no value since Windows 2000.

The ones which only remove safe stuff are a waste of time, and if you paid for one, a waste of cash too.

The ones which promise to make your system go faster actually do that but not by good means. They cripple the system to the point where you have to re-install from scratch.. after they have asked for cash to fix themselves and the bogus errors they told you about to scare you..

If you still think that registry cleaners are a good, go ahead and get one.

Gordon is correct.

Lead3 is correct.

Palcouk is correct.

TrekDozer is correct.

Microsoft have even withdrawn their registry cleaner [their Installer cleanup utility] because it sometimes had unwanted side-effects - they now only recommend individual fixes targetted at specific problems. What greater confirmation is needed about the dangers of registry cleaners than this?

Investigating & correcting specific problems is better than potentially writing off the entire system through use of these unpredictable "tools".

By the way, you've worded your comments as though you were addressing Microsoft. This is not Microsoft. This is a peer-to-peer mutual support forum where users ask questions and users answer questions.