In my personal experiences, you always can have two ways to go on here:
1). Send a message to all of the email addresses.
As everyone mentions above, in this case, you can directly send a message to all of these addresses and see whether they are valid.
2). Apply a special email verifier to take chances.
If you think the first way is not so practical and efficient, you also can apply a special email verifier to take chances.
I have ever tried this free one named Dr Email Verifier:
This verifier always can help easily check the validity of your entered email addresses in seconds. Moreover, its “Batch Mode” will also help check a batch of email addresses at once. What you need to do is only to import them rightly.
I hope this works for you.