I recently inserted my USB drive to my PC because I wanted to transfer new pictures that I got from another computer (not mine). As soon as I did this, Trend Micro Titanium detected a virus...
If the other computer was infected, connecting even a freshly-formatted flash drive to it can immediately infect the flash drive. When you connect the flash drive to your computer, your computer can immediately become infected, too.
Your best bet is to destroy & throw away that flash drive then don't connect any other flash drives to the other computer (or any flash drive that's been connected to the other computer to your computer).
Please contact TrendMicro Support for any further guidance you need to questions you may have - or you could begin your own, new thread in this forum => http://community.trendmicro.com/t5/Titanium/bd-p/titanium-forum