I had not seen this reply from you when I wrote my first post. If your uninstall attempt is generating a runtime error then it implies that DataSafe is not merely installed but it is actively monitoring your computer for things to backup. This also explains why it is sometimes generating those has stopped working messages.
Start DataSafe and look through its settings to find out what you have it doing in the background.
While you are in DataSafe you can check its Help file for instructions on making the DFIR USB backup I mentioned before.
My own version of DataSafe was from 2010 so the interface might have changed since then. In my version, I selected the button labelled Backup on the left-hand side of the window and then selected Create recovery media. That started the one-time process of backing up the DFIR partition onto USB [or DVD but USB should be more reliable]. The Help system should explain that better than I can as I removed the utility several years ago [but have retained the DFIR USB backup].