Hi All,
Thank you for all the help provided.
I ended up doing full windows reinstall - turns out that this have solved the case.
Reason below:
Whilst I've installed the game on the first instance it came up with an error which I've tried to solve using informations from various forums (including copying some dll files etc).
Unfortunately I must have caused some issues with .net framework.
I have mentioned in posts above that I have re-build the .net framework, however I was under the impression that only latest .net framework will need re-installing (4.6).
Turns out that game requires .net 3.5 (which is included in Windows but need an update upon launching the game).
As I've messed up (I think) my .net 3.5 on the first instance, the uplay game launcher never prompted me to get the 3.5 updated.
After Windows re-install I have downloaded and installed the game again and immidietly I was promped to update .net 3.5.
Since then both games are running without any problems.