Hi.
I think you have two options to fix that problem:
Option One.- Try to downloading the lastest version of Xpadder.
Option Two.- Try to uninstall or update your XBOX 360 controller's and Touchpad's drivers by doing the following steps:
1.- Right click on Windows Start Icon and select Device Manager.
2.- Once Device Manager is opened, expand Mice and other pointer devices and Game Controllers.
3.- Every driver that is in Display, right click and select Update Driver Software.
4.- A window will be opened. Choose Search automatically for a update driver software.
5.- Once the installation of your drivers are completed, restart your PC and try running Xpadder again.
Hope this helped.