Loretta,
Thanks for making it clear what the question (at least yours) is actually about. The way it was worded originally plainly confused a lot of would-be helpers.
Also, many of the 37 posters on this thread are discussing a different issue altogether: how scammers may tell you to use the Run command.
There are some third-party utilities that can be used for this (see discussion here: https://jpsoft.com/forums/threads/activating-the-run-dialog.4741/ ), but you can also do it by creating a shortcut that opens the Run command and then assigning a keyboard shortcut.
Given that the original thread started 5 years ago, I don't know if you are using Windows XP or a more recent version of Windows.
If you have Windows 7 or 8, see the directions here --> http://www.sevenforums.com/tutorials/21246-run-command-create-shortcut.html
If you have Windows XP, create a Shortcut to the Run command by clicking on "Run" in the Start Menu and dragging it to the Desktop or to the Quick Launch toolbar. See http://www.techrepublic.com/article/create-a-run-command-shortcut/ After the shortcut has been created, pick up with Step 4 of Method 2 of the Windows 7/8 directions above.
Before clicking OK after you have set the shortcut to open "minimized," click near "None" next to "Shortcut key" and type a single letter (e.g., R) or number. Then click OK. Your keyboard shortcut will be CTRL+ALT+the letter you typed. See http://www.vistax64.com/tutorials/74063-keyboard-shortcut.html (should work for XP also).
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Oops! Sorry, I didn't catch that you use Windows 10 until I typed all of the above. I'm not going to delete it, just in case someone who has XP, 7, or 8 wants to know. You can get the Run command on the Windows 10 Start Menu by following these directions -->
http://www.tekrevue.com/tip/windows-10-start-menu-run-command/
http://winaero.com/blog/add-run-to-start-menu-in-windows-10-rtm/
I don't have Win 10, so I can't experiment to see if you can then create a keyboard shortcut as described for Windows 7/8.