(1) A clean install might be a good idea to be rid of accumulated junk & ASUS bloatware that may have come with the computer. Especially if it came with McAfee or such that has tentacles all over the place & could be tough to be completely rid of otherwise.
Windows Defender is built in & is sufficient, I think. But ASUS may have other big things in there too equally duplicative or otherwise unnecessary . You might check for an ASUS recovery partition that could return the computer to factory state & decide whether
you want to keep it. I got rid of mine that would have returned this Dell back to Win 8.1.
Here's a big write-up...
https://answers.microsoft.com/en-us/windows/forum/windows_10-windows_install/clean-install-windows-10/1c426bdf-79b1-4d42-be93-17378d93e587
Clean Install Windows 10
(2) But maybe start with a repair-install that keeps all files & 3rd-party apps to see whether it is a sufficient cure...
(a) Make a Windows system image,
at "START, Settings, Update & Security, Backup, Go to Backup & Restore (Win 7)", in case things get worse.
Make the Repair Disc to restore it with, or ask Cortana for "Recovery Drive" to make it on USB. Also, see...
https://www.winhelp.us/restore-a-system-image-in-windows-7.html
Restore a System Image Backup in Windows 7, 8, 8.1 and 10
Note1: That's a 3rd-party site. The literature looks good. I know nothing of the links or downloads there.
Note2: For added assurance, it could be good to use 3rd-party imaging software as well. If you have a Seagate or Maxtor HDD, there is a free version of Acronis at their site. Seagate calls it DiscWizard. These are faster, more flexible,
& make more compact images. Macrium Reflect & AOMEI Backupper also have free versions.
(b) Download Win 10 Installation media & do the repair-install...
https://www.microsoft.com/en-us/software-download/windows10
Download Windows 10 - Currently, this is v.1803
Make a Win 10 Installation USB drive or burn an .iso to DVD.
As the article says, match it to the Edition (Home, Pro, etc.),
Language, & Architecture (64-bit/x64 or 32-bit/x86) of the computer on which it will be used.
Instructions are at the site how to use those to do an upgrade. Since you already are version 1803, this will be a repair-install. Basically, you boot to Windows,
plug in the media, open it in File Explorer, & click
Setup.exe. It will run a bit over an hour. Here are the screens you might see...
https://answers.microsoft.com/en-us/windows/forum/windows_10-windows_install/how-to-upgrade-to-windows-10-version-1803-spring/617a37da-8fc0-4f33-a3eb-59fe9082f925?messageId=a241803d-31c3-4720-b0e4-9002a989ea3c
How to Upgrade to Windows 10 Version 1803 Spring Creators Update Using ISO File from Versions 1709, 1703, 1607, 1511 or 1507
Edit: Oops. Here is what I was thinking of for the repair-install...
https://www.tenforums.com/tutorials/16397-repair-install-windows-10-place-upgrade.html
How to Do a
Repair Install of Windows 10 with an In-place Upgrade
But it says, "The installation media (ex:
ISO or
USB) must be the
same edition and same or newer build as your currently installed Windows 10. If it's not, then the repair install will fail."
So - sounds like it might not work. The download likely is a lesser OS Build than you've got. Sorry.