Ok, I have found the solution to this problem.
I opened Disc Managment and found the two drives for the Lexar Dual Card Slot reader (one for SD cards and one for CF cards) . I noted that there was no drive letter for either. I right clicked on each and selected change drive letter and a drive letter was selected for both. Now my card reader is showing up in file explorer and seems to be working fine. No idea how this happened, but I assume it may have occur ed during an update of some kind.
Thanks for your help Susan!
Kind regards,
Kelly