Thanks for all your input, perhaps I need to be a little more specific in my question.
What I specifically want to know, is:
Does windows clean up the temp folder as a housekeeping task when a computer is rebooted (i.e. if I was to use software in the morning after a fresh reboot, and that software does not create a 'temp folder', would it mean that the software would not be able to find the windows temp folder?
Hope this is a little clearer.
Thanks again!