So, I noticed there are only Windows 7 and earlier drivers listed for this make and model.
Here are some updates I recommend you download and apply.
BIOS Update December 2016
https://dlcdnets.asus.com/pub/ASUS/mb/SocketAM3...
Audio Realtek audio driver May 2016
https://dlcdnets.asus.com/pub/ASUS/misc/audio/R...
Try installing the audio driver in compatibility mode:
Run Old Software on Windows 10 with Compatibility Mode - groovyPost
https://www.groovypost.com/howto/run-old-softwa...
Check if it then works.
Note: This is a non-Microsoft website. The page appears to be providing accurate, safe information. Watch out for ads on the site that may advertise products frequently classified as a PUP (Potentially Unwanted Products). Thoroughly research any product advertised on the site before you decide to download and install it.