Hi 777. I'm Greg, an installation specialist, 10 year Windows MVP, and Guardian Moderator here to help you.
For USB drive not detected, first try steps here: https://mspoweruser.com/solved-usb-device-not-r...
Right click Start to open Disk Management, scroll down on map to look for USB drive, if found then right click to assign a drive letter so it shows up in File Explorer.
Right click Start to open Device Manager to look for the drive under Disk Drives. It may be listed by it's model or Serial which you can google to determine which is it. Click on the Device, then Driver tab, choose Roll Back if available. If not then choose Uninstall, restart PC to reinstall driver.
If no newer or this doesn't help, then go to the USB category in Device Manager, open each Enhanced, Hub and Host controller, from Driver tab select Roll back if available, or if not choose Uninstall.
If your keyboard and mouse are USB, first program the power button to effect the needed restart after Rolling back or uninstalling the driver. Go to Settings > System > Power & Sleep > Additional Power Settings > Choose what Power buttons do to choose Shutdown.
Test the drive using diagnostics to know for sure it's condition: https://www.lifewire.com/free-hard-drive-testin...
Follow this up with a DIsk Check from the Command Prompt if necessary: https://www.groovypost.com/howto/check-hard-dri...
Run the Hardware Troubleshooter at Settings > Update & Security > Troubleshoot.
You can check which Updates were installed just before this happened, then uninstall them at Settings > Update & Security > Windows Update > Installed Update History - look first for installed drivers. Then you can hide these Updates using the Hide Updates tool: https://www.howtogeek.com/224471/how-to-prevent...
You can also try to System Restore to a point before this happened, then check for Updates using the Hide Updates Tool to block the Updates offered: http://home.bt.com/tech-gadgets/computing/how-t...
Check if the drive is detected in another PC. If so back up the data to it's desktop.
Then plug it back into the PC which cannot detect it, reformat in Disk Management:
http://www.wikihow.com/Format-an-External-Hard-...
I hope this helps. Feel free to ask back any questions and let us know how it goes. I will keep working with you until it's resolved.
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