Hi, Shawna1972!
My name is Caio. I'm an Independent Advisor and I'll be glad to help you today.
Let me try to understand your question a bit better: you have 2 mouses and keyboards and you want to be able to use them, one at a time, to control things on your Windows?
If that's what you asked, yes it's possible. Just make sure the wired mouse is on a flat surface so it won't move the cursor accidentaly while you're using the wireless one.
But if you want to control two different things simultaneously you'll need a third party solution.
I hope this helps you! Please let me know if I can assist you more.
Best regards,
Caio G.
Independent Advisor