I don't know how it might work, like I said I just thought it might need a driver during install for some reason. Perhaps you can ask on the Gigabyte forum. Reading your last post you don't mean you are trying to install onto the USB but you mean it doesn't show the internal drive to install Windows 10.
Is that what you mean. Windows 10 install media is already on the USB and you boot from it and then select Language > Install now > Custom install, at custom install you do not see the internal drive?
I assume if you go into the bios you can see the internal drive listed there. Have you disconnected all other USB storage devices and you only have one internal drive to install onto.