Hi Vet. I'm Greg, awarded MVP for eleven years, Volunteer Moderator, and Independent Advisor here to help you until this is resolved.
I'll give you everything possible to try for USB dysfunction which we see a lot here:
Update your Chipset and USB drivers from the PC maker's Support Downloads web page for your full model number, HP Serial Number, or Dell Service tag from the sticker on PC.
Compare the latest drivers with the ones presently installed in Device Manager reached by right clicking the Start Menu. Make sure you have the latest BIOS, Chipset, Display (Video), Sound, USB3, Bluetooth, Network and all other drivers, or else download and install the latest now.
If no newer or this doesn't help, then go to the USB category in Device Manager, open each Enhanced, Hub and Host controller, from Driver tab select Roll back if available, or if not choose Uninstall.
If your keyboard and mouse are USB, first program the power button to effect the needed restart after Rolling back or uninstalling the driver. Go to Settings > System > Power & Sleep > Additional Power Settings > Choose what Power buttons do to choose Shutdown.
Finally find the drive under USB or other device categories, right click to Uninstall Driver, restart PC to reinstall the driver.
If it still doesn't show up, is it read in another PC? If so copy it's files into a folder on the desktop, move it back to the problem PC, wipe and then format the drive in Disk Management:
http://www.howtogeek.com/235824/how-to-clean-a-...
I hope this helps. Feel free to ask back any questions and keep me posted. If you'll wait to rate whether my post helped you, I will keep working with you until it's resolved.
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