Hi,
If your Windows 10 hotkeys are disabled for some reason, here's how to bring them back:
Press Windows Key + R to open the Run dialog, type gpedit.msc into the dialog box, then press Enter to access the Local Group Policy Editor.
Head to User Configuration > Administrative Templates > Windows Components > File Explorer.
Open Turn off Windows Key hotkeys.
Select Disabled or Not Configured.
Click Apply to save the new settings.
Hope that works for you.
If that is not the case, please kindly attach a screen-shot of the issue so we could work towards resolving it.
Regards,
Lee