Hi, Drew. I'm Robinson, and I’m happy to help you today.
The Microsoft SDK is additional software installed with Visual Studio. Before deleting this folder, you must ensure you have uninstalled the Microsoft SDK to avoid further errors.
1-Right-Click on Start then click on Run
2-Type: Control Panel and click on OK
3-Click on "Uninstall a program"
4-Search on the list for "Microsoft Windows SDK" or "Windows SDK AddOn" and uninstall them
When you make sure you have uninstalled the Microsft SDK, you can delete the "Microsoft SDKs" folder.
I hope this information helps. If you have any questions, please let me know and I'll be glad to assist you further.