I have been trying to figure out how to find my computers serial number because i need to activate windows on my new motherboard but every time I try to find it, it only says to be filled by O.E.M
O.E.M. means Original Equipment Manufacturer.
What I think is happening, here, is that the OP purchased a pre-fabricated (HP or Dell or whatever) PC from somebody, then swapped out the Motherboard to turn it into "a custom" PC. What OP really did was remove the BIOS which contained the O.E.M. embedded license key for Windows.
The new motherboard may or may not even have the ability to embed a license key in this manner, and probably does not. If it did, the only way to get back the old license key would be to reinstall the old motherboard and then there's maybe a 2% chance that the OEM license key for Windows can be viewed and written down for manual input, maybe through that BIOS.