Hi. I'm Brian and I will do my best to help you.
OneDrive is integral to Windows. In what way does it "screw up" your system? By default, the folders Documents, Pictures and Desktop will be synched to the online OneDrive cloud, but you can certainly disable that.
I somehow lost an install for a program. The main problem is that I did not know the files were being sent to onedrive and several programs lost file as they are now scattered all over the machine instead of where I had them directed. I WOULD NOT HAVE HAD A PROBLEM IF ONEDRIVE WAS NOT INSTALLED WITHOUT MY CONSENT!
I hate how Microsoft pushes some programs and useless features but don't fix known issues. How about fix Microsoft security or at least concentrate on that as their enterprise users could lose billions. I am so frustrated I think I will upgrade to Apple as the end of windows 10 is coming. At least they seem to be interested in user security.