I swear that you're not alone, man..I have been searching for it since year 2021...until now, there is still no checkbox found, not to say any solution for this. Only keyboard is functioning by default (without ticking or adjusting any setting) after I displaying wirelessly through Samsung DEX, but neither usb mouse nor touchpad on the laptop is working.
Personally, I dont think its the problem of SAMSUNG DEX. The checkbox mentioned by the system as well as in the reply of @Zack_DP to this thread is not found on any of my setting. @Zack_DP please provide a better solution for this, since this problem is persisted for YEARS. Improve or solve the bugs please.