Hello @Tomas Gil , , currently the Graph API only supports calling data. To open it with a desktop application, the only thing I can think of is to use GET /drives/{drive-id}/items/{item-id}
to get @microsoft.graph.downloadUrl
Download the file and then open it with the desktop application, or you can submit a feature request idea using this support link, which will be monitored by Microsoft team and make the enhancements to Microsoft Graph APIs. I will also upvote for you. I hope it can help you.
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