This blog will show you how to do it. https://www.recastsoftware.com/resources/how-to-create-an-anti-malware-policy-for-endpoint-protection/
Disable Defender realtime scan or stop defender

Ranjithkumar Duraisamy
231
Reputation points
Is there any article to describe, disable defender or stop real-time protection through SCCM antimalware policies or so?
Microsoft Security | Intune | Configuration Manager | Other
4,608 questions
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Rahul Jindal 10,911 Reputation points MVP
2022-07-13T21:50:06.66+00:00 What is end objective here? Stopping AV like this will lower the security of the devices. If you are trying to troubleshoot or exclude something then there may be other ways to achieve this.