A family of Microsoft spreadsheet software with tools for analyzing, charting, and communicating data.
Take a look at the "Benefits of the New File Formats" section here:
http://msdn.microsoft.com/en-us/library/aa338205(v=office.12).aspx
If none of the benefits are things you're interested in, there's no reason to change.
In general, .xlsx/.xlsm files are somewhat less likely to become corrupt, and can be smaller, but if you make regular backups and have plenty of disk space, there's no reason to spend the time converting.
OTOH, there's usually no reason not to take advantage of the OOXML formats for new files that you create.