A family of Microsoft word processing software products for creating web, email, and print documents.
I don't want to give you a flat "no" for an answer, but Word really wasn't designed to do that kind of work. The experience would be time-consuming and frustrating, and the documents would be hard to maintain. You could probably cobble together the navigation links, but the page turning effect won't be possible in Word.
Instead, look into software that is specifically intended for the job: http://www.google.com/search?q=software+for+creating+ezine.
You can certainly write the text for your manuals in Word for ease of editing, and then paste the final version into the ezine software.