Hi @Phillip Johnson ,
Welcome to Microsoft Q&A!
If you are debugging ASP.NET application, please refer to: Remote Debug ASP.NET on a Remote IIS Computer and check if the requirements are met.
Meanwhile, please ensure that the version of ASP.NET used in your app is the same as the version you installed on the server.
You can update your VS2022 to the latest version through Visual Studio Installer and try to restart IIS process.
For ASP.NET Core application, you can refer to: Remote Debug ASP.NET Core on a Remote IIS Computer in Visual Studio.
Sincerely,
Anna
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