Hi,
Thank you for your question and reaching out.
I understand that you have a query regarding the compatibility for HTTP Server API in Windows. The answer to your question is YES. You just have to make sure that the requirements have been met and make sure to also enable the TLS 1.2 on the site servers and remote site systems. You may refer to the links below for more information regards to that:
https://learn.microsoft.com/en-us/mem/configmgr/core/plan-design/security/enable-tls-1-2-server
https://learn.microsoft.com/en-us/mem/configmgr/core/plan-design/security/enable-tls-1-2-client
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