Hi @Ashwan ,
In order to enable secure connection and when connect as a best practice, recommend that in the connection string used by the application, you specify an encrypted connection and not trust the server certificate. This forces your application to verify the server certificate and thus prevents your application from being vulnerable to man in the middle type attacks.
transparent-data-encryption-tde-overview
Note: TDE cannot be used to encrypt system databases, such as the master database, in Azure SQL Database and Azure SQL Managed Instance. The master database contains objects that are needed to perform the TDE operations on the user databases. It is recommended to not store any sensitive data in the system databases. Infrastructure encryption is now being rolled out which encrypts the system databases including master.
Please refer to TLS section (Encryption in transit & Encryption in motion) of this documentation
Hope this information will help. Please let us know in case of further queries. Thanks.