Hi @Nilesh Mahesh Verma ,
You can install the latest cumulative update depending on your version.
Here are the build versions of SQL Server 2016: KB3177312 - SQL Server 2016 build versions
You can upgrade SP2-GDR to SP3 and then install GDR.
Please see this image to help you have a better understanding.
Note: GDR (General Distribution Release) is different from CU. Each latest CU contains cumulative updates based on RTM/SP. GDR only contains serious updates.
Best regards,
Seeya
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