As far as I know, there is no related known issues has been offered.
Once you upgrade your PC to the latest Windows version your Prolific USB to Serial Driver also updates to the latest driver software and if the driver is not compatible with your Hardware issues may arise, you will have to download the driver again by following these steps:
Right-click on your PC Start button and open Device Manager
Double click LPT and COM ports then locate the Prolific USB to Serial Driver and right-click it so you can select Update Driver
For driver software click My computer
From My computer select "Let me pick from a list of drivers available"
Choose an older version from the list then click Next
The driver you selected will be installed automatically
Once it has been downloaded reconnect the driver to see if it works.
Hope above information can help you.
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