From an excel perspective, I want to confirm that do these Excel files contain macros?
If you can download these Excel files, please download it to local machine, and right-click them > Propertities > Make sure these files are not blocked.
Then go to File > Info, check whether you can select Remove protection.
Besides, does this issue occur with other Office files, such as Word documents?
Please double click the the email > Message > Actions > Edit Message, check whether the attachments still be opened as read-only.
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