Hi @Alan Koop ,
Thanks for your feedback above which shared more information and glad to know that your issue is resolved now! Since our forum has the policy that the question author cannot accept their own answer. They can only accept answers by others, and according to the scenario introduced here: Answering your own questions on Microsoft Q&A
I would make a brief summary of this post so that other forum members could easily find useful information here:
[Activating lagged copies - Summary]
One User Cannot Send E-mails via Outlook or Webmail
The user's Windows account was corrupt. Remove the profile and re-connect.
You could "Accept Answer" for this summary to close this thread, and your action would be helpful to other users who encounter the same issue and read this thread. Thanks for your understanding!