Hi,
This should be possible however will not be supported by Microsoft if any issues arises out of the deployment as it is open source CA and Issuing CA, so just to keep a note of this. However there is detailed thread and guidance from third party blogger on this and might help you - https://4sysops.com/archives/use-openssl-based-software-xca-as-offline-root-certificate-authority-for-ad-certificate-services/
Hope this helps.
JS
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