Hello A.Elrayes,
Initially this implmentation is related to specific requirements of compliance, mostly for government organizations within the US. Unless there is a compliance requirement in your organization it is not mandatory to be installed.
NIST SP 800-171 is a NIST Special Publication that provides recommended requirements for protecting the confidentiality of controlled unclassified information (CUI). Defense contractors must implement the recommended requirements contained in NIST SP 800-171 to demonstrate their provision of adequate security to protect the covered defense information included in their defense contracts, as required by DFARS clause 252.204-7012. If a manufacturer is part of a DoD, General Services Administration (GSA), NASA or other federal or state agencies’ supply chain, the implementation of the security requirements included in NIST SP 800-171 is a must.
There should not be no issue expected after enabling, since it only specifies a encryption standard to be uses specifically. BitLocker is FIPS-validated, but it requires a setting before encryption that ensures that the encryption meets the standards set forth by FIPS 140-2
To enable, the machine needs to be decrypted (read as: Drives unencrypted and Bitlocker disabled) then:
Open Local Security Policy as administrator
Navigate to Local Policies => Security Options
Set System Cryptography: Use FIPS compliant algorithms for encryption, hashing, and signing to be Enabled
Then, encrypt the machine using BitLocker
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