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Yes, one physical server can be configured with a VDI role. In order to do so, you will need to install and configure the appropriate hypervisor software such as VMware vSphere or Microsoft Hyper-V. After the hypervisor software is installed, you can then configure the server to host multiple virtual machines, each of which can be configured with the appropriate VDI roles and settings. Additionally, you will need to configure the server's storage and networking to ensure that it has sufficient resources to support your VDI environment.
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