You can try the solution in this link, FIX: "MMC has detected an error in a snap-in" when a non-administrator starts SNA Manager in Host Integration Server, and the IIS SMTP Virtual Server component has been permanently deprecated on July 14, 2015, so I recommend you to deprecate it. more information you can refer to this link: configure-smtp-e-mail-in-iis-7-and-above.
Besides, you can also try this method:
- Stop SMTPSVC service [Display Name: Simple Mail Transfer Protocol (SMTP)]
- Stop IISADMIN service [Display name: IIS Admin Service]
- Edit "C:\Windows\System32\inetsrv\MetaBase.xml"
- Find: <IIsSmtpServer Location ="/LM/SmtpSvc/1"
- Add (Settings are alphabetical): RelayIpList=""
- Save file
- Start IISAdmin Service
- Start SMTPSVC service
More information you can refer to this link: https://serverfault.com/a/1115389.
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